Ora Calibra® Lid Swelling Scales

Our standardized Clinician Grading Scale employs reference panoramic videography of the eyelids, a more sensitive technique than photography.

Eyelid edema can be caused by a variety of different ocular inflammatory pathologies and can lead to vision obstruction as well as to problems with a patient’s quality of life. Eyelid edema is quite prevalent, as recent estimates suggest that between 20 and 40 million Americans suffer some form of acute or chronic eyelid edema disease.

The highly variable and patient-specific nature of eyelid edema makes the development of clinician grading scales problematic. Studies assessing allergic eyelid edema have shown the patient to be capable of effectively grading their own edema, based on familiarity with their appearance. Still, clinician-grading using standardized scales have failed, even with the aid of reference photographs. For this reason, Ora has developed its standardized Ora Calibra® Clinician Grading Scale using reference panoramic videography of the eyelids, a more sensitive technique than photography, and has tested it in a population of subjects with morning eyelid edema.

The Ora Calibra® Subjective Lid Swelling Scale asks the patients to grade their eyelid swelling in an absolute manner. The second subjective scale refers to a baseline time point, where a - 4 indicates a maximum worsening compared to the baseline time point, and a + 4 indicates a maximum improvement. The Konica Minolta 3D laser scanner is a light based topography technique which can be used to attain changes in volumetric swelling. This new objective videography based grading scale visually quantifies how eyelid edema increases while subjects are asleep and decreases over the course of the day. Further, this is supported by subjective scales as well as a volumetric reading device. This videography scale places the assessment of eyelid edema severity in the hands of an objective clinician. With this instrument, Ora is now screening various agents that can reduce existing eyelid edema.